CEFO-S injection
MANUFACTURER/ MARKETER
C Pharmaceuticals
SALT COMPOSITIONCefuroxime (1000mg) + Sulbactam (500mg)
STORAGE
Store below 30°C
Product introduction
CEFO-S Injection is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.
CEFO-S Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of CEFO-S Powder for Injection
Description of Bacterial infections
Definition
Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it.
Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.
Useful Bacteria
Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food.
Some examples of good bacteria include:
1. Lactobacillus is used in making yogurt and cheese.
2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K.
3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization.
Causes and Risk Factors
Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur:
1. Pharyngitis -- Streptococcus pyogenes
2. Diphtheria -- Corynebacterium diphtheria
3. Pertussis -- Bordetella pertussis
4. Tuberculosis -- Mycobacterium tuberculosis
Gastrointestinal infections caused by bacteria include:
1. Peptic ulcers -- Helicobacter pylori
2. Enteric (typhoid) fever -- Salmonella typhi
3. Gastroenteritis -- Shigella, Salmonella, and Escherichia coli
Bacteria cause infections of the nervous system such as:
1. Meningitis -- Streptococcus pneumonia and Neisseria meningitidis
2. Tetanus -- Clostridium tetani
3. Botulism -- Clostridium botulinum
Urogenital infections caused by bacteria include:
1. Urinary tract infections -- Escherichia coli
2. Gonorrhea -- Neisseria gonorrhoeae
3. Chlamydia -- Chlamydia trachomatis
4. Syphilis -- Treponema pallidum
Bacteria also cause skin infections such as:
1. Leprosy -- Mycobacterium leprae
2. Abscess -- Staphylococcus aureus
Signs and Symptoms
The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.
Investigations
The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include:
1. Physical examination
2. Blood tests
3. Urine tests
4. Urine culture
5. Gram stain to identify bacteria
6. Toxin assay to look for the toxins made by the bacteria
7. Culture or biopsy of the tissue infected
Treatment
The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include:
1. Amoxicillin
2. Azithromycin
3. Doxycycline
4. Ofloxacin
5. Tetracycline
6. Gentamycin
7. Metronidazole
8. Clindamycin
Supportive therapy may be required for other symptoms, such as fever.
Complications and When Should You See a Doctor
The complications will depend on the kind of bacterial infection.
Antibiotics must be taken carefully and for the duration, they are prescribed for. Taking them too frequently, taking them without a prescription or not completing the full course of treatment may lead to a development of antibiotic resistance, where antibiotics fail to kill bacteria.
Antibiotic resistance makes treatment of bacterial infections difficult and may prolong the illness and severity.
References
Fernández-Frackelton M. Bacteria. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA:Elsevier; 2018:chap 121.
McAdam AJ, Milner DA, Sharpe AH. Infectious diseases. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 8.
Benefits of CEFO-S Powder for Injection
In Bacterial infections
CEFO-S Injection works by killing bacteria which can cause bacterial infections. It is used to treat many different types of bacterial infections. It is given by a doctor or nurse into a vein and should not be self-administered.CEFO-S Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Side effects of Cefos-S Powder for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cefos-S
- Nausea
- Vomiting
- Diarrhea
- Increased liver enzymes
- Allergic reaction
How to use CEFO-S Powder for Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How CEFO-SPowder for Injection works
CEFO-S Injection is a combination of two medicines: Cefuroxime and Sulbactam. Cefuroxime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Sulbactam is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate Cefuroxime. Addition of Sulbactam reduces resistance and enhances the activity of Cefuroxime against bacteria.
Safety advice
Consuming alcohol with CEFO-S Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
CEFO-S Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
CEFO-S Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Not relevant, as CEFO-S Injection is intended for use in hospitalised patients.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of CEFO-S Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of CEFO-S Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Cefos-S Powder for Injection?
If you miss a dose of CEFO-S Injection, please consult your doctor.
