AXICIN 100/250/500injection
MANUFACTURER/ MARKETER
C Pharmaceuticals
SALT COMPOSITION
Amikacin (500mg)
STORAGE
Store below 30°C
Product introduction
AXICIN 100/250/500 Injection is an antibiotic used to prevent or treat a wide variety of bacterial infections. These may include infections of the urinary tract, bones, and joints, lungs (eg. pneumonia), brain, blood, among others. It is also used in hospitalized patients to prevent infections.
AXICIN 100/250/500 Injection works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional and should not be self-administered. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Common side effects of this medicine include injection site reactions and increased blood urea. Consult your doctor if any of these side effects persist or if your condition does not improve despite treatment.
Some patients receiving high doses may develop balance disorder (loss of balance), kidney damage, and hearing loss. Therefore, please follow all the instructions given by your doctor while using this medicine. Your doctor may also monitor you with regular kidney function tests, hearing tests, and urine tests during treatment. This medication is not recommended for use during pregnancy. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Uses of AXICIN 100/250/500 Injection
Description of Bacterial infections
Definition
Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it.
Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.
Useful Bacteria
Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food.
Some examples of good bacteria include:
1. Lactobacillus is used in making yogurt and cheese.
2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K.
3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization.
Causes and Risk Factors
Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur:
1. Pharyngitis -- Streptococcus pyogenes
2. Diphtheria -- Corynebacterium diphtheria
3. Pertussis -- Bordetella pertussis
4. Tuberculosis -- Mycobacterium tuberculosis
Gastrointestinal infections caused by bacteria include:
1. Peptic ulcers -- Helicobacter pylori
2. Enteric (typhoid) fever -- Salmonella typhi
3. Gastroenteritis -- Shigella, Salmonella, and Escherichia coli
Bacteria cause infections of the nervous system such as:
1. Meningitis -- Streptococcus pneumonia and Neisseria meningitidis
2. Tetanus -- Clostridium tetani
3. Botulism -- Clostridium botulinum
Urogenital infections caused by bacteria include:
1. Urinary tract infections -- Escherichia coli
2. Gonorrhea -- Neisseria gonorrhoeae
3. Chlamydia -- Chlamydia trachomatis
4. Syphilis -- Treponema pallidum
Bacteria also cause skin infections such as:
1. Leprosy -- Mycobacterium leprae
2. Abscess -- Staphylococcus aureus
Signs and Symptoms
The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.
Investigations
The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include:
1. Physical examination
2. Blood tests
3. Urine tests
4. Urine culture
5. Gram stain to identify bacteria
6. Toxin assay to look for the toxins made by the bacteria
7. Culture or biopsy of the tissue infected
Treatment
The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include:
1. Amoxicillin
2. Azithromycin
3. Doxycycline
4. Ofloxacin
5. Tetracycline
6. Gentamycin
7. Metronidazole
8. Clindamycin
Supportive therapy may be required for other symptoms, such as fever.
Benefits of AXICIN 100/250/500 Injection
In Bacterial infections
AXICIN 100/250/500 Injection is the injection form of an antibiotic medicine that stops the growth of the infection-causing bacteria in your body. It is often injected by a doctor or a nurse either into a vein or a muscle. This medicine is used to treat many different types of infections such as urinary tract, bones and joints, lungs (eg. pneumonia), brain, blood, and some others. This medicine usually makes you feel better within a few days. Follow your doctor's instructions carefully to get maximum benefit.
Side effects of AXICIN 100/250/500 Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
How AXICIN 100/250/500 Injection works
AXICIN 100/250/500 Injection is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
Safety advice
Consuming alcohol with AXICIN 100/250/500 Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
AXICIN 100/250/500 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
AXICIN 100/250/500 Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
AXICIN 100/250/500 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
AXICIN 100/250/500 Injection should be used with caution in patients with kidney disease. Dose adjustment of AXICIN 100/250/500 Injection may be needed. Please consult your doctor.
AXICIN 100/250/500 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Amikacin AXICIN 100/250/500 Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take AXICIN 100/250/500Injection?
If you miss a dose of AXICIN 100/250/500 Injection, please consult your doctor.
