CEFINEC 250/500/1000

CEFINEC 250/500/1000 injection
MANUFACTURER/ MARKETER
C Pharmaceuticals
SALT COMPOSITION
Ceftriaxone (1gm) + Sulbactam (500mg)
STORAGE
Store below 30°C

Product introduction

CEFINEC 250/500/1000  Injection is a combination medicine. It is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.

CEFINEC 250/500/1000 Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of CEFINEC 250/500/1000 Injection

Description of Bacterial infections

Definition

Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it.
Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.

Useful Bacteria

 

Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food.
Some examples of good bacteria include:
1. Lactobacillus is used in making yogurt and cheese.
2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K.
3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization.

 

Causes and Risk Factors

Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur:

1. Pharyngitis -- Streptococcus pyogenes

2. Diphtheria -- Corynebacterium diphtheria

3. Pertussis -- Bordetella pertussis

4. Tuberculosis -- Mycobacterium tuberculosis

Gastrointestinal infections caused by bacteria include:

1. Peptic ulcers -- Helicobacter pylori

2. Enteric (typhoid) fever -- Salmonella typhi

3. Gastroenteritis -- Shigella, Salmonella, and Escherichia coli

Bacteria cause infections of the nervous system such as:

1. Meningitis -- Streptococcus pneumonia and Neisseria meningitidis

2. Tetanus -- Clostridium tetani

3. Botulism -- Clostridium botulinum

Urogenital infections caused by bacteria include:

1. Urinary tract infections -- Escherichia coli

2. Gonorrhea -- Neisseria gonorrhoeae

3. Chlamydia -- Chlamydia trachomatis

4. Syphilis -- Treponema pallidum

Bacteria also cause skin infections such as:

1. Leprosy -- Mycobacterium leprae

2. Abscess -- Staphylococcus aureus

 

Signs and Symptoms

 

The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.

 

Investigations

 

The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include:

1. Physical examination

2. Blood tests

3. Urine tests

4. Urine culture

5. Gram stain to identify bacteria

6. Toxin assay to look for the toxins made by the bacteria

7. Culture or biopsy of the tissue infected

 

Treatment

 

The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include:
1. Amoxicillin
2. Azithromycin
3. Doxycycline
4. Ofloxacin
5. Tetracycline
6. Gentamycin
7. Metronidazole
8. Clindamycin
Supportive therapy may be required for other symptoms, such as fever.

 

Complications and When Should You See a Doctor

 

The complications will depend on the kind of bacterial infection.
Antibiotics must be taken carefully and for the duration, they are prescribed for. Taking them too frequently, taking them without a prescription or not completing the full course of treatment may lead to a development of antibiotic resistance, where antibiotics fail to kill bacteria.
Antibiotic resistance makes treatment of bacterial infections difficult and may prolong the illness and severity.

 

References

 

Fernández-Frackelton M. Bacteria. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA:Elsevier; 2018:chap 121.
McAdam AJ, Milner DA, Sharpe AH. Infectious diseases. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 8.

 

Benefits of CEFINEC 250/500/1000 Injection

CEFINEC 250/500/1000 Injection contains two different medicines, Ceftriaxone and Sulbactum, that work together to kill the bacteria that cause infections. Ceftriaxone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Ceftriaxone against bacteria.
CEFINEC 250/500/1000 Injection can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of CEFINEC 250/500/1000 Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of CEFINEC 250/500/1000

• Diarrhea
• Increased liver enzymes
• Allergic reaction
• Rash

How to use CEFINEC 250/500/1000 Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer. 

How CEFINEC 250/500/1000 Injection works

CEFINEC 250/500/1000 Injection is a combination of two medicines: Ceftriaxone and Sulbactam. Ceftriaxone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Ceftriaxone against bacteria.

Safety advice

Alcohol

SAFE

Consuming alcohol with CEFINEC 250/500/1000 Injection does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

CEFINEC 250/500/1000 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

CEFINEC 250/500/1000 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

CEFINEC 250/500/1000 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of CEFINEC 250/500/1000 Injection in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

CEFINEC 250/500/1000 Injection should be used with caution in patients with severe liver disease. Dose adjustment of CEFINEC 250/500/1000 Injection may be needed. Please consult your doctor.
Dose adjustment of CEFINEC 250/500/1000 Injection is not recommended in patients with mild to moderate liver disease.

 

What if you forget to take CEFINEC 250/500/1000 Injection?

If you miss a dose of CEFINEC 250/500/1000 Injection, please consult your doctor.