1-CLAV-625
1-CLAV-625mg Tablet
MANUFACTURER/ MARKETER
C Pharmaceuticals
SALT COMPOSITION
Amoxycillin (500mg) + Clavulanic Acid (125mg)
STORAGE
Store below 30°C
PRODUCT INTRODUCTION
1-CLAV-625 Tablet is a penicillin-type of antibiotic that helps your body fight infections caused by bacteria. It is used to treat infections of the lungs (e.g., pneumonia), ear, nasal sinus, urinary tract, skin, and soft tissue. It will not work for viral infections such as the common cold.
1-CLAV-625 Tablet is best taken with a meal to reduce the chance of a stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back or worsen.
The most common side effects of this medicine include vomiting, nausea, and diarrhea. These are usually mild but let your doctor know if they bother you or will not go away.
Before taking it, let your doctor know if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know about all other medicines you are taking as they may affect, or be affected by, this medicine. This medicine is generally regarded as safe to use during pregnancy and breastfeeding if prescribed by a doctor.
USES OF 1-CLAV-625 TABLET
Description of Bacterial infections
Definition
Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it. Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.
Useful Bacteria
Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food. Some examples of good bacteria include:
1. Lactobacillus is used in making yogurt and cheese.
2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K.
3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization.
Causes and Risk Factors
Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur:
1. Pharyngitis -- Streptococcus pyogenes
2. Diphtheria -- Corynebacterium diphtheria
3. Pertussis -- Bordetella pertussis
4. Tuberculosis -- Mycobacterium tuberculosis
Gastrointestinal infections caused by bacteria include:
1. Urinary tract infections -- Escherichia coli
2. Gonorrhea -- Neisseria gonorrhoeae
3. Chlamydia -- Chlamydia trachomatis
4. Syphilis -- Treponema pallidum
Bacteria also cause skin infections such as:
1. Leprosy -- Mycobacterium leprae
2. Abscess -- Staphylococcus aureus
Signs and Symptoms
The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.
Investigations
The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include:
1. Physical examination
2. Blood tests
3. Urine tests
4. Urine culture
5. Gram stain to identify bacteria
6. Toxin assay to look for the toxins made by the bacteria
7. Culture or biopsy of the tissue infected
Treatment
The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include:
1. Amoxicillin
2. Azithromycin
3. Doxycycline
4. Ofloxacin
5. Tetracycline
6. Gentamycin
7. Metronidazole
8. Clindamycin
Supportive therapy may be required for other symptoms, such as fever.
Complications and When Should You See a Doctor
The complications will depend on the kind of bacterial infection.
Antibiotics must be taken carefully and for the duration, they are prescribed for. Taking them too frequently, taking them without a prescription or not completing the full course of treatment may lead to a development of antibiotic resistance, where antibiotics fail to kill bacteria.
Antibiotic resistance makes treatment of bacterial infections difficult and may prolong the illness and severity.
References
Fernández-Frackelton M. Bacteria. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA:Elsevier; 2018:chap 121. McAdam AJ, Milner DA, Sharpe AH. Infectious diseases. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 8.
BENEFITS OF 1-CLAV-625 TABLET
In Treatment of Bacterial infections
1-CLAV-625 mg Tablet contains two different medicines, Amoxycillin and Clavulanic Acid, that work together to kill the bacteria that cause infections. Amoxycillin works by stopping the growth of bacteria. Clavulanic Acid reduces resistance and enhances the activity of Amoxycillin against bacteria.
This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
SIDE EFFECTS OF 1-CLAV-625 TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of 1-CLAV-625
- Vomiting
- Nausea
- Diarrhea
HOW TO USE 1-CLAV-625mg TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. 1-CLAV-625 625mg Tablet is to be taken with food.
HOW 1-CLAV-625mg TABLET WORKS
1-CLAV-625 mg Tablet is a combination of two medicines: Amoxycillin and Clavulanic Acid. Amoxycillin is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Amoxycillin against bacteria.
SAFETY ADVICE
1-CLAV-625mg Tablet may cause side effects such as allergic reactions, dizziness or fits that may make you unfit to drive.
Use of this medicine is not recommended in patients with severe kidney disease.
Regular monitoring of liver function tests is recommended while you are taking this medicine
WHAT IF YOU FORGET TO TAKE 1-CLAV-625mg TABLET?
If you miss a dose of 1-CLAV-625mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.