CROCIF-O Tablet
MANUFACTURER/ MARKETER
C Pharmaceuticals
SALT COMPOSITION Cefixime (200mg) + Ofloxacin (200mg)
STORAGE
Store below 30°C
Product introduction
CROCIF-O Tablet is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.
CROCIF-O Tablet is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of CROCIF-O Tablet
Description of Bacterial infections
Definition
Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it.
Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.
Useful Bacteria
Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food.
Some examples of good bacteria include:
1. Lactobacillus is used in making yogurt and cheese.
2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K.
3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization.
Causes and Risk Factors
Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur:
1. Pharyngitis -- Streptococcus pyogenes
2. Diphtheria -- Corynebacterium diphtheria
3. Pertussis -- Bordetella pertussis
4. Tuberculosis -- Mycobacterium tuberculosis
Gastrointestinal infections caused by bacteria include:
1. Peptic ulcers -- Helicobacter pylori
2. Enteric (typhoid) fever -- Salmonella typhi
3. Gastroenteritis -- Shigella, Salmonella, and Escherichia coli
Bacteria cause infections of the nervous system such as:
1. Meningitis -- Streptococcus pneumonia and Neisseria meningitidis
2. Tetanus -- Clostridium tetani
3. Botulism -- Clostridium botulinum
Urogenital infections caused by bacteria include:
1. Urinary tract infections -- Escherichia coli
2. Gonorrhea -- Neisseria gonorrhoeae
3. Chlamydia -- Chlamydia trachomatis
4. Syphilis -- Treponema pallidum
Bacteria also cause skin infections such as:
1. Leprosy -- Mycobacterium leprae
2. Abscess -- Staphylococcus aureus
Signs and Symptoms
The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.
Investigations
The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include:
1. Physical examination
2. Blood tests
3. Urine tests
4. Urine culture
5. Gram stain to identify bacteria
6. Toxin assay to look for the toxins made by the bacteria
7. Culture or biopsy of the tissue infected
Treatment
The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include:
1. Amoxicillin
2. Azithromycin
3. Doxycycline
4. Ofloxacin
5. Tetracycline
6. Gentamycin
7. Metronidazole
8. Clindamycin
Supportive therapy may be required for other symptoms, such as fever.
Complications and When Should You See a Doctor
The complications will depend on the kind of bacterial infection.
Antibiotics must be taken carefully and for the duration, they are prescribed for. Taking them too frequently, taking them without a prescription or not completing the full course of treatment may lead to a development of antibiotic resistance, where antibiotics fail to kill bacteria.
Antibiotic resistance makes treatment of bacterial infections difficult and may prolong the illness and severity.
Benefits of CROCIF-O Tablet
In Treatment of Bacterial infections
CROCIF-O Tablet is a combination of two different antibiotics that work together, in different ways, to treat various bacterial infections. Cefixime works by stopping the growth of bacteria and kills them. Ofloxacin prevents multiplication and repair of infection causing bacteria and prevents further spread of the infection.
This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Side effects of CROCIF-O Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Severe side effects of CROCIF-O
- Insomnia (difficulty in sleeping)
- Dizziness
- Headache
- Hypersensitivity
- Hypereosinophilia
- Agranulocytosis (deficiency of granulocytes in the blood)
- Decreased white blood cell count (lymphocytes)
- Decreased white blood cell count (neutrophils)
- Granulocytopenia
- Hemolytic anemia
- Low blood platelets
- Thrombocytosis
- Gastrointestinal disturbance
- Increased liver enzymes
- Increased bilirubin in the blood
- Increased blood urea
- Pseudomembranous colitis
- Jaundice
- Acute renal failure
- Breathlessness
- Seizure
- Inflammation of tendons
- Tendon rupture
- Serum sickness
- Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome
- Itching
- Rash
- Drug fever
- Joint pain
- Erythema multiforme
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Paresthesia (tingling or pricking sensation)
- Psychotic disorder
- Visual disturbance
How to use CROCIF-O Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CROCIF-O Tablet may be taken with or without food, but it is better to take it at a fixed time.
How CROCIF-O Tablet works
CROCIF-O 200mg/200mg Tablet is a combination of two antibiotics: Cefixime and Ofloxacin. Cefixime works by preventing the formation of the bacterial protective covering which is essential for the survival of the bacteria in the human body. Ofloxacin works by preventing the bacteria from reproducing and repairing themselves. Together, they treat your infection effectively.
Safety advice
It is unsafe to consume alcohol with CROCIF-O Tablet.
Pregnancy
CONSULT YOUR DOCTOR
CROCIF-O Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
CROCIF-O Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CROCIF-O Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CROCIF-O Tablet should be used with caution in patients with kidney disease. Dose adjustment of CROCIF-O Tablet may be needed. Please consult your doctor.
CROCIF-O Tablet should be used with caution in patients with liver disease. Dose adjustment of CROCIF-O Tablet may be needed. Please consult your doctor.
